acentric chromosome造句

Acentric chromosome fragments may arise in a variety of ways.
Micronuclei originating from chromosome loss events and acentric chromosome fragments can be distinguished using pancentromeric DNA probes.
Micronuclei form during anaphase from lagging acentric chromosome or chromatid fragments caused by incorrectly repaired or unrepaired DNA breaks or by nondisjunction of chromosomes.
If DNA damage exceeds the repair capacity of the cell, unrepaired double-stranded DNA breaks may also result in acentric chromosome fragments.
That acentric chromosome fragment may segregate with the intact chromatid and result in partial tetrasomy; or, it may segregate with the complementary broken chromatid and result in partial trisomy because the broken chromatid may be saved by telomere restitution.
It's difficult to find acentric chromosome in a sentence. 用acentric chromosome造句挺难的

Another way eccentric chromosome fragments may arise is when defects in genes related to homologous recombinational repair ( ex : ATM, BRCA1, BRCA2, and RAD51 ) result in a dysfunctional error-free homologous recombinational DNA repair pathway and causes the cell to resort to the error-prone non-homologous end-joining ( NHEJ ) repair pathway, increasing the likelihood of incorrect repair of DNA breaks, formation of dicentric chromosomes, and acentric chromosome fragments.